HAPPY OR SAD: THE CHEMISTRY BEHIND DEPRESSION

“The human life is made up of choices. Yes or No. In or Out. Up or Down. Live or Die. Hero or Coward. I’ll say it again to make sure you hear me. The human life is made up of choices. Live or die. That’s an important choice. And it’s not always in our hands.”

-Derek Shepherd, Season 6, Episode 24.

Genetic makeup influences how sensitive you are to stressful life events. When genetics, biology, and stressful life situations come together, depression can result.

Stress has its own physiological story with a chain of chemical reactions and responses in the body. 

People with suicidal thoughts exhibit higher levels of Translocator Protein, associated with microglial activation and indicating inflammation of the brain in a region of the cortex which is involved in emotional processes.

The long story of stress causes the low secretion of Serotonin ‘the happy neurotransmitter’, which increases the higher risk of suicide

Dopamine, ‘the motivational chemical’ and Noradrenaline, ‘fight-to-fight chemical’ acts as ‘magical wand’ to reinforce pleasure.

Our thoughts regulate chemical processes. We can’t let negativity dominate us. 

The loss of creative soul, Sushi Bhai who won hearts through ‘ Chichore’ actually sparked mainstream media to talk about ‘ Mental Illness’. We need to make ‘therapy’ the ‘New Norm’. It’s okay not to be okay!